SKU: 41089256395

Aminated hollow Prussian blue nanoparticles

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Description

Aminated hollow Prussian blue nanoparticlesProduct Name Name: Aminated hollow Prussian blue nanoparticles Product Overview Prussian Blue (PB for short), also known as Teng's Blue or Ferrocyanide, is a polymeric complex composed of three elements: C, N, and Fe. It generally refers to Ferrocyanide, and its molecular formula is Fe4 [Fe (CN) 6] 3. PB can be used as an antidote for the treatment of thallium and cesium poisoning, and has good biological safety. PB is synthesized by aging

Product Name

Name:Aminated hollow Prussian blue nanoparticles

Product Overview

Prussian Blue (PB for short), also known as Teng's Blue or Ferrocyanide, is a polymeric complex composed of three elements: C, N, and Fe. It generally refers to Ferrocyanide, and its molecular formula is Fe4 [Fe (CN) 6] 3. PB can be used as an antidote for the treatment of thallium and cesium poisoning, and has good biological safety.

PB is synthesized by aging crystallization of potassium ferrocyanide and polyvinylpyrrolidone (PVP). The reaction mainly involves the coordination of CN bonds in potassium ferrocyanide with Fe3+and Fe2+to form crystal nuclei, while PVP is doped with its own CN bonds to form a crystalline structure. Hollow mesoporous Prussian blue (HMPB) is prepared by etching PB with hydrochloric acid, and the cavity structure can be used to load drugs to improve tumor treatment efficiency.

Technical Parameter

Diameter:0-150nm

Solvent:water

Appearance:Blue liquid

Concentration:mg/mL

Product Features

1. Good dispersibility: The raw material PVP, as an amphiphilic substance, is easily soluble in water, resulting in PB with good water dispersibility.

2. Good drug loading capacity: The hollow mesoporous structure obtained by etching of this product has a large surface area and pore volume, which can be used as a nanocarrier to load small molecular substances such as drugs and genes, meeting different biomedical needs.

3. Multiple nano enzyme activities: PB has POD enzyme activity and can decompose H2O2 to produce hydroxyl radicals (· OH); Has SOD enzyme activity and can catalyze the production of H2O2 and O2 from peroxyl groups (· OOH); It has CAT activity and can decompose H2O2 to produce O2.

4. Excellent photothermal conversion efficiency: PB has good light absorption ability at 808 nm, which can convert light energy into heat energy. The generated heat can ablate tumor cells, and the increase in temperature can also enhance nanoenzyme activity.


Application Fields

1. Drug loading: PB, due to its unique hollow mesoporous structure, can load chemotherapy drugs, improve drug loading rate, and achieve targeted drug delivery through surface modification of targeted molecules, thereby improving therapeutic efficacy and slowing down drug side effects on normal cells.

2. Photothermal therapy: PB, due to its special lattice structure, has near-infrared light absorption characteristics and biological safety, and has been widely studied as a new type of photothermal conversion material in the application of tumor ablation.

3. Nanoenzyme therapy: PB has various nanoenzyme activities, such as POD, SOD, CAT enzyme activities, which can clear free radicals, slow down inflammation, alleviate oxidative stress reactions, catalyze hydrogen peroxide to produce oxygen, and alleviate tumor hypoxia.

4. Biomedical imaging: PBNPs have good magnetic resonance imaging (MRI) and photoacoustic imaging (PA) characteristics. At the same time, due to the advantages of their mesoporous structure and surface modification, fluorescence imaging and ultrasound imaging based on PB structure have also been synergistically used for disease diagnosis, leveraging the advantages of multimodal imaging.

Related Information

Please e-mail for the detailed characterization data.

E-mail:[email protected]

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★★★★★ 4
A good read
Format: Kindle
Multiple points of view. 3 Alpha men and an Omega male. She is a Beta in training for a new program placing betas in Alpha/Omega packs. Mila is only doing the program for the money to take care of her dad. She wasn't expecting to fall for a pack but when she sees this packs Omega she is done for. There is just something about him. His Alphas are good looking as well. Too bad she is hiding a secret and their government is acting shady. I liked it and can't wait to see where their story goes.
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Reviewed in the United States on November 14, 2023
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Bri Hires
Lexington, US
★★★★★ 3
Slightly repetitive but I did love some things
Format: Kindle
I love this type of story. And omegaverse is one of my all time favorite genres. But there are a few things that pulled me out of my enjoyment while I was reading. It was repetitive at times as well as struggled with telling not showing. So we didn’t always feel like we were experiencing things with the main character. There were also some plot holes but they may still be answered in part 2. Now this isn’t to be said I didn’t enjoy parts of the story. I loved the almost instant love between Mila and Oliver. And how he started changing around her.
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Reviewed in the United States on February 15, 2024
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Kimberly G
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★★★★★ 5
delightful read
Format: Kindle
What a delightful read. The characters are awesome, the plot was so good, I loved it. I was intrigued and it kept me wanting more. Told in multiple pov, the book sucks you in and doesn’t let go. I cannot wait to read the next book.
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Reviewed in the United States on January 30, 2025
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Kimberly B
Port Orchard, US
★★★★★ 4
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Reviewed in the United States on November 17, 2023
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Carmen Alicea
Los Angeles, US
★★★★★ 5
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In Spare, Violet Fox flips the omegaverse on its head, giving us a Beta heroine determined to make her mark. Joining the Beta Trials to support her sick father, she's thrown into a pack that doesn't want her, especially the possessive Alphas. But here's the twist: their sweet Omega turns out to be her scent match. Cue the angst, forbidden tension, and a slow-burn romance that will make your heart ache in the best way. Violet Fox delivers an emotional, refreshing take on the genre, proving Betas aren't "spares." They're stars.
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