SKU: 10021472757

TUBA1B Rabbit Polyclonal Antibody

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Description

TUBA1B Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen TUBA1B Synonyms Tubulin alpha 1B chain; Alpha tubulin ubiquitous; Tubulin K alpha 1; Tubulin alpha ubiquitous chain Immunogen Synthetic Peptide Location Cytoplasm, Cytoskeleton Accession P68363 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P, ICC Reactivity Hu, Ms, Rt, Mk Positive Sample HEK 293, HeLa, MCF7, NIH 3T3, PC 12, COS 7 Purification Immunogen Affinity Concentration 0. 5 mg ml

Product Specification


Host Rabbit
Antigen TUBA1B
Synonyms Tubulin alpha-1B chain; Alpha-tubulin ubiquitous; Tubulin K-alpha-1; Tubulin alpha-ubiquitous chain
Immunogen Synthetic Peptide
Location Cytoplasm, Cytoskeleton
Accession P68363
Antibody Type Polyclonal antibody
Isotype IgG
Application WB, IHC-P, ICC
Reactivity Hu, Ms, Rt, Mk
Positive Sample HEK-293, HeLa, MCF7, NIH/3T3, PC-12, COS-7
Purification Immunogen Affinity
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu, Ms, Rt, Mk
IHC-P 1:1000 Hu, Ms, Rt
ICC 1:500 Hu, Ms

Background

TUBA1B (tubulin alpha-1B chain) is a ubiquitously expressed cytoskeletal protein that polymerizes with beta-tubulin to form microtubules, thereby orchestrating mitotic spindle assembly, intracellular transport, cell shape and motility; its over-expression is frequently observed in multiple cancers where it drives proliferation, migration and invasion, correlates with advanced stage and poor survival, modulates innate and adaptive immune signaling, and predicts response to immune-checkpoint inhibition, making it an emerging prognostic biomarker and potential therapeutic target.

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SKU: 10021472757

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