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Description
Insulin Recombinant Rabbit mAb (S-638-19)Product Specification Host Rabbit Synonyms INS Immunogen Synthetic Peptide Location Secreted Accession P01308 Clone Number S 638 19 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Predicted Reactivity Cz, Or Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of
Product Specification
| Host | Rabbit |
| Synonyms | INS |
| Immunogen | Synthetic Peptide |
| Location | Secreted |
| Accession | P01308 |
| Clone Number | S-638-19 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Cz, Or |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:2000 |
Background
Insulin is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the INS gene. It is considered to be the main anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of glucose from the blood into liver, fat and skeletal muscle cells. Proinsulin is cleaved into insulin and C-peptide. The two are stored in the secretory granules of the pancreatic β-cells and eventually released together in equimolar amounts. C-peptide has an important role in facilitating the correct folding of insulin and formation of its disulfide bridges.
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