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Description
S-RMab® PU.1 Recombinant Rabbit mAb (SDT-R236)Product Specification Host Rabbit Synonyms Transcription factor PU. 1, 31 kDa transforming protein, SPI1 Location Nucleus Accession P17947 Clone Number SDT R236 Antibody Type Recombinant mAb Isotype IgG Application IHC P, ICC, ICFCM Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of
Product Specification
| Host | Rabbit |
| Synonyms | Transcription factor PU.1, 31 kDa-transforming protein, SPI1 |
| Location | Nucleus |
| Accession | P17947 |
| Clone Number | SDT-R236 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IHC-P, ICC, ICFCM |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:500 | |
| ICC | 1:500 | |
| ICFCM | 1:500 |
Background
Transcription factor PU.1 is a protein that in humans is encoded by the SPI1 gene. The PU.1 transcription factor is essential for hematopoiesis and cell fate decisions. PU.1 can physically interact with a variety of regulatory factors like TFIID, GATA-2, GATA-1 and c-Jun. The protein-protein interactions between these factors can regulate PU.1-dependent cell fate decisions. PU.1 can modulate the expression of 3000 genes in hematopoietic cells including cytokines. It is expressed in monocytes, granulocytes, B and NK cells but is absent in T cells, reticulocytes and megakaryocytes. Its transcription is regulated by various mechanisms.
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4.3 ★★★★★
Based on 372 reviews
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Product Reviews
★★★★★ 5
On the fence? This is the sheepskin to get!
Size: 2' x 3' (Natural), Color: Wolf Tipped
I've been reading all the reviews for sheepskins on AMZ and felt this company was the one to go for and WOW did they deliver! The sheepskin came well wrapped but not vacuum packed and is even prettier in person than the pictures. It is super soft, fluffy and dense and mine measured 26" x 40". I absolutely love the wolf tipped colors: ivory, dark grey and a slight brownish hue. There is a slight odor but I don't find it offensive. It stayed put on my leather couch and sitting on it during a Netflix movie was heavenly warm and comfortable. I did not observe any shedding. Will definitely buy another wolf tipped one, once it becomes available as it is worth the money.
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Reviewed in the United States on January 14, 2026
★★★★★ 5
Gorgeous 😍
Size: 2' x 6' (Natural), Color: Champagne, Size: 2' x 6' (Natural), Color: Champagne
Absolutely beautiful!!! It is thick and luxurious, super soft and cozy. It’s really high quality and it shows. You can tell it’s natural without the burn test even from its cute little curls. All brushed (your pet brush is perfect 😉) out it looks stunning and fluffy. I got the champagne color and I love it! I don’t see any seams on the double pelt and it is substantial, not at all like it will disintegrate in a few years, but rather will become a much loved family heirloom. Well worth the investment! It is absolutely heavenly to perform yoga on by the fire 😌I love taking my slippers off and feeling the soft fur. I don’t want to get off it lol. I understand all those other customer’s kids and cats 🤣😂🤣
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Reviewed in the United States on November 26, 2023
★★★★★ 5
This is the one you want...
Size: 2' x 6' (Natural), Color: Natural (Yellow Undertones), Size: 2' x 6' (Natural), Color: Natural (Yellow Undertones)
I bought a ‘Genuine Sheepskin Rug Double Pelt Natural White Fur 2x6’ from Amazon in 2011 for $112.49, and recently decided to recommission it in my new living room. It looked so nice that I decided to add a second rug, and was pleased to find what Amazon claimed to be the same rug still available for only $83.78. Now I’m not one of those silly folks who expects the color and/or size of a natural product like a sheepskin rug to be perfectly predictable, and my living room is large enough that I didn’t need the two rugs to match perfectly, but when the new rug arrived, I couldn’t have been more disappointed. It was about 40% smaller than my older rug, was way, way off from anything that could be called white, and looked cheap, old, and tattered. I tried to comb it out a bit to see if I could make it look presentable, but it was a lost cause.
Amazon to the rescue. I returned the rug to Amazon for a full refund the next morning, and the transaction couldn’t have been simpler. And I immediately ordered the ‘Genuine Sheepskin Rug Double Pelt Natural White Fur 2x6’ shown on this page from Super Area Rugs for $119.00. What a difference! These rugs are large, plush, and super soft. The quality of these rugs is obvious, much, much nicer that either my old sheepskin rug or the ‘bargain’ rug I returned to Amazon. I was so impressed with the quality of this rug that I immediately ordered a second, which arrived this morning (it matches the other rug perfectly). My older sheepskin has been reassigned to another room because, well, it’s not in the same league as my two new rugs, which look terrific together.
As is so often the case, you get what you pay for. So if you’re looking for a top quality sheepskin rug, this is the one you want.
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Reviewed in the United States on December 23, 2015
★★★★★ 4
Very nice fleeces
This is a clean, soft, well groomed fleece intended for use on a 6 foot long sofa, so bought 2. They moved too much as a result of shifting bodies on the leather couch, so will get a longer version, sewn bottom to bottom, and used each of these fleeces on both armrests, instead.
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Reviewed in the United States on August 15, 2025
★★★★★ 5
Excellent Product!!! Will purchase again!
Size: 2' x 3' (Natural), Color: Wolf Tipped
Instead of ordering a cover for reclining loveseats, I chose to drape one of these over the headrest on either end of our loveseat. Not only do they protect the leather, they also help to elevate our decor. The rugs were received in a very timely manner. They are super soft, & warming as we move into the winter months. We've had family & friends comment on how great they look. 2 of them have already ordered, & added them to their sofa/loveseat/recliner decor. Have an issue of them slipping, add some velcro in between the crook of the cushion & the back of the furniture piece. It doesn't show & will help to keep the rug in place; if your busy body.!
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Reviewed in the United States on December 10, 2025