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Description
CD42b Recombinant Rabbit mAb (SDT-R147)Product Specification Host Rabbit Antigen CD42b Synonyms GPIb, Platelet glycoprotein Ib alpha chain, GPIb alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b alpha Immunogen N A Location Membrane Accession P07359 Clone Number SDT R147 Antibody Type Recombinant mAb Application IHC P, IF Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 25 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300
Product Specification
| Host | Rabbit |
| Antigen | CD42b |
| Synonyms | GPIb, Platelet glycoprotein Ib alpha chain, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha |
| Immunogen | N/A |
| Location | Membrane |
| Accession | P07359 |
| Clone Number | SDT-R147 |
| Antibody Type | Recombinant mAb |
| Application | IHC-P, IF |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.25 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:1000 | null |
| IF | 1:250 | null |
Background
Platelet glycoprotein Ib alpha chain also known as glycoprotein Ib (platelet), alpha polypeptide or CD42b (Cluster of Differentiation 42b), is a protein that in humans is encoded by the GP1BA gene. Glycoprotein Ib (GPIb) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The GpIb functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V to form the glycoprotein Ib-IX-V complex. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis.
Shipping Notes
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Exchange/Return Notes
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