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Description
Anti-PD-1 Monoclonal Antibody(Nivolumab)Product Specification Host Human Antigen PD 1 Synonyms Programmed cell death protein 1, Protein PD 1, hPD 1, CD279, PDCD1 Accession Q15116 Clone Number S SC016 Antibody Type Recombinant mAb Isotype IgG4,k Application Blocking of PD 1 PD L signaling Functional assays Purification Protein A Concentration 2 mg ml Endotoxin <1EU mg Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4, containing no preservative Stability & Storage
Product Specification
| Host | Human |
| Antigen | PD-1 |
| Synonyms | Programmed cell death protein 1, Protein PD-1, hPD-1, CD279, PDCD1 |
| Accession | Q15116 |
| Clone Number | S-SC016 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG4,k |
| Application | Blocking of PD-1/PD-L signaling Functional assays |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| ELISA | 0.305-5000 ng/ml |
Background
Nivolumab is a type of targeted therapy drug called an immune checkpoint inhibitor (a type of immunotherapy). It is a monoclonal antibody that binds to the protein PD-1 on the surface of immune cells called T cells. It works by keeping cancer cells from suppressing the immune system. This allows the immune system to attack and kill the cancer cells.
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4.4 ★★★★★
Based on 1631 reviews
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Product Reviews
★★★★★ 5
A must buy for the littles this winter.
Format: Kindle
Frostfire is a must buy for the littles this winter. I read through it once myself and absolutely loved the story and especially the illustrations. A very classic, winter whimsy.
The second time I read Frostfire was with my 3 and 5 year olds. They also enjoyed it and had quite the debate over whether the snow dragon would be real. The 3 year old won!
Looking forward to this book's release and coming across some frostfire in the real world this winter.
Thanks to Penguin Random House Canada, Tundra Books and NetGalley for the eARC!
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Reviewed in the United States on October 13, 2024
★★★★★ 4
atmospheric illustrations and a story about sharing imagination
Format: Hardcover
I received this book as part of the LibraryThing EarlyReviewer program. The illustrations are photographs of collage, with some digital editing to add snow effects. It's a bit of an atmospheric "kids go for a walk in the snow" book, a la The Snowy Day, but for older kids. I liked how there was a subtle background story about children trying to navigate having slightly conflicting imaginative stories. It can be a challenge for a kid to learn how to do this when playing with others. The illustrations of the dragon especially were a wonderful surprise. My 8 year old loved the book and is happy that we get to keep it.
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Reviewed in the United States on December 13, 2024
★★★★★ 5
A Glittery Fantasy
Format: Hardcover
The author's sparkling illustrations highlight this magical tale of two fox sisters and their grand adventure in a snowy wonderland. What begins as a mild prank played by the older sister on the younger turns out to be a spectacular reality . . . or does it? This is a lovely salute to the imagination and the joys of childhood.
Many thanks to the publisher for sharing.
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Reviewed in the United States on November 16, 2024
★★★★★ 5
Stunning Illustrations, wonderful story
Format: Kindle
I was immediately drawn to this book by the bewitching title and exquisite artwork. We follow two sisters, Celeste and Miriam, on their garden adventure in the magical snow.
This story was the perfect length, with enchanting drawings and an adorable plot with charming sisters.
Such a joy to read I will definitely be looking forward to reading this book with my daughter. I could see it being a winter favorite.
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Reviewed in the United States on October 13, 2024
★★★★★ 5
If you have sensitive skin and dont want premium prices, Cremo’s body wash is an excellent option A+
Scent: Palo Santo, Size: 16 Fl Oz (Pack of 1), Scent: Palo Santo, Size: 16 Fl Oz (Pack of 1)
Cremo’s body wash for men has become a staple in our household. The product exudes a luxurious feel, from the rich lather to the clean, long-lasting scent that genuinely resembles a more expensive fragrance.
This body wash possesses a pleasant aroma of cardamom, papyrus, and most notably, palo santo. It features a warm, woody, and spicy scent, which is one of my preferred fragrance notes. Notably, the scent is strong without being overpowering. Additionally, I appreciate the aesthetic appeal of the bottle. The exquisite and vintage-inspired packaging complements the fragrance effectively.
What truly sets Cremo’s body wash apart is its gentle nature. I have sensitive skin and this body wash does not cause dryness or irritation. In fact, it leaves my skin feeling soft and smooth, which is not always the case with other brands I have tried.
The affordability of Cremo’s body wash is a significant advantage. It offers a high-end feel and fragrance without incurring excessive costs, making it an easy choice for repeat purchases. If you or your family have sensitive skin or simply desire a pleasant scent without paying premium prices, Cremo’s body wash is an excellent option.
Highly Recommended. 5/5 Stars.
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Reviewed in the United States on October 5, 2025