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Ships within 48 hours · Estimated delivery Jul 8 - Jul 13
For Your Every Summer RSVP, with Code: SUMMER15
Description
Langerin Recombinant Rabbit mAb (SDT-450-47)Product Specification Host Rabbit Antigen Langerin Synonyms C type lectin domain family 4 member K, CD207, CLEC4K Immunogen Synthetic Peptide Location Membrane Accession Q9UJ71 Clone Number SDT 450 47 Antibody Type Recombinant mAb Isotype IgG Application IHC P Reactivity Hu Purification Protein A Concentration 0. 25 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability &
Product Specification
| Host | Rabbit |
| Antigen | Langerin |
| Synonyms | C-type lectin domain family 4 member K, CD207, CLEC4K |
| Immunogen | Synthetic Peptide |
| Location | Membrane |
| Accession | Q9UJ71 |
| Clone Number | SDT-450-47 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IHC-P |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.25 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:1000 |
Background
Langerin (CD207) is a type II transmembrane C-type lectin which is encoded by the CD207 gene in humans. Langerin is known to be associated with the formation of Birbeck granules in Langerhans cells (LCs). LCs are immune cells closely related to macrophages, but by their function, they are more like conventional dendritic cells (cDCs). Langerin is a highly selective marker for Langerhans cells and the lesional cells of Langerhans cell histiocytosis.
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