SKU: 78035831958

PKR Recombinant Rabbit mAb (S-731-118)

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Description

PKR Recombinant Rabbit mAb (S-731-118)Product Specification Host Rabbit Antigen PKR Synonyms Interferon induced, double stranded RNA activated protein kinase; Eukaryotic translation initiation factor 2 alpha kinase 2 (eIF 2A protein kinase 2); Interferon inducible RNA dependent protein kinase; P1 eIF 2A protein kinase; Protein kinase RNA activated (PKR; Protein kinase R); Tyrosine protein kinase EIF2AK2; p68 kinase; PRKR; EIF2AK2 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus

Product Specification


Host Rabbit
Antigen PKR
Synonyms Interferon-induced, double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2 (eIF-2A protein kinase 2); Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein kinase; Protein kinase RNA-activated (PKR; Protein kinase R); Tyrosine-protein kinase EIF2AK2; p68 kinase; PRKR; EIF2AK2
Immunogen Synthetic Peptide
Location Cytoplasm, Nucleus
Accession P19525
Clone Number S-731-118
Antibody Type Recombinant mAb
Isotype IgG
Application WB, ICC
Reactivity Hu
Positive Sample MCF7, HEK-293, K562, HeLa, HepG2, Jurkat
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu
ICC 1:500 Hu

Background

PKR, also known as Protein Kinase R or double-stranded RNA-dependent protein kinase, is a serine/threonine catalytic enzyme that plays a crucial role in innate immune responses against viral infections. It is an interferon-induced kinase that can be activated by double-stranded RNA (dsRNA), a common byproduct of viral replication. Once activated, PKR phosphorylates the eukaryotic initiation factor 2α (eIF2α), which inhibits protein synthesis and viral replication. Additionally, PKR can activate the NF-κB signaling pathway, enhancing the expression of antiviral genes. Beyond its antiviral functions, PKR is involved in various cellular processes, including apoptosis, cell growth, and differentiation. Its dysregulation has been implicated in several diseases, including cancer, making it a potential therapeutic target.

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SKU: 78035831958

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4.2 ★★★★★
Based on 29 reviews
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Product Reviews
M
Verified Purchase
Mrs. C .Russell
Lake Worth, US
★★★★★ 5
Nice iPad Keyboard
Color: Marine Blue
My son enjoys his iPad more since he attached this keyboard. It's the perfect size, but the key is to read the specifications. He has yet to complain about a lapse in typing to seeing what he has typed so the keyboard responds well. Unfortunately, he has dropped the keyboard a few times, but thankfully it has proven to breable to withstand his roughness. The magnetic aspect of the keyboard is a nice feature and the keyboard stays in place as it should. My son does not charge the keyboard daily and he said that the lifespan of the battery is good and it lasts for several days. Although you can't compare this small keyboard to the comfort of a desktop computer keyboard, it doesn't pose any problems while typing and it gets the job done.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 15, 2026
A
Verified Purchase
alecia
Draper, US
★★★★★ 5
Perfect Keyboard Case | Works Great !!!
Color: Light Pink, Color: Light Pink
Got it for my iPad 11th gen. Love love the case. It does feel a little heavy with the iPad in it but that’s okay for me. The keyboard connects instantly to my iPad. There are no glitches when typing and keys feel comfy. I love the different lights that come with the keyboard. Overall, it’s perfect
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 7, 2026
K
Verified Purchase
Kayla K
West Palm Beach, US
★★★★★ 4
Good case, I’d recommend, but a few things to consider…
Color: Light Pink
I got this while it was on sale, I’d say it’s worth the money. The case itself feels nice and is functional in the aspects it says it should be. My only complaint is that it is a bit difficult to type, especially with how small the keyboard is. However, it makes sense why the keyboard is small because it’s the same size as the iPad (horizontal width wise). The color is very nice, and I really enjoy the different light options for the keyboard. The case is a bit heavy, but it’s still portable and wouldn’t be a hassle to carry around. Another thing that I didn’t quite realize when buying is that you can’t close the case with the keyboard attached, it has to be unattached for it to close. That a little annoying because I have to find a safe spot for it aside, but I suppose the perk of that is that you don’t have to have the keyboard attached to the case to use it since it is Bluetooth. Overall, good case and keyboard, and id recommend if you’re looking for something functional, easy, and affordable.
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Reviewed in the United States on December 31, 2025
A
Verified Purchase
Arely Covarrubias
Massapequa, US
★★★★★ 5
Good quality
Color: Light Pink, Color: Light Pink
This one it’s my favorite case, it makes my iPad a little computer, I love it and well this is my favorite color, good price for what you get, the keyboard syncs fast no problem and I also like that the keyboard changes color
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Reviewed in the United States on May 15, 2026
M
Verified Purchase
Michael V
Dallas, US
★★★★★ 5
Great product for the price and it's cute!
Color: Light Pink, Color: Light Pink
I bought this because I wanted to type easier on my iPad and all the other keyboards I looked up were a bit pricey. I saw this one on sale for a good price and decided to buy it. They had it in a few different colors and light pink was one of them so I got it because it's my favorite color. The quality of the color, and the outside case is pretty great, no imperfections, it looks really solid. The keyboard itself is quite thin and lightweight, when you press the keys you can see it dip in the middle a bit but that doesn't bother me too much. Don't type to heavy because it could potentially cause issues, we'll see if in the future after many uses if it does cause any issues. The magnet isn't super strong but it does hold it in place when you put the keyboard more towards the bottom of the front flap of the case. It does seem a bit cheap but the price is also cheap so it makes sense. As long as it works well and lasts long, then I'm satisfied. The colors do change, the button for that is on the bottom row of keys and the key has three circles with 'R' 'G' and 'B' as well as a brightness key to it's left labeled with a light bulb. Connecting it to the iPad was quick and easy too, simply turn on your Bluetooth and look for new device connection in the Bluetooth settings, press the 'connect' button on the keyboard and once it turns blue then check for 'Typecase Folio' it connects quickly and easily. Happy typing!
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Reviewed in the United States on August 31, 2024

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