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Description
p120 Catenin Recombinant Rabbit mAb (SDT-350-75)Product Specification Host Rabbit Antigen p120 Catenin Synonyms Catenin delta 1; Cadherin associated Src substrate; CAS; p120 catenin; p120(ctn); p120(cas) Immunogen Synthetic Peptide Location Cell membrane, Cytoplasm Accession O60716 Clone Number SDT 350 75 Antibody Type Recombinant mAb Application ICFCM, IHC P, ICC, WB, IF Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid
Product Specification
| Host | Rabbit |
| Antigen | p120 Catenin |
| Synonyms | Catenin delta-1; Cadherin-associated Src substrate; CAS; p120 catenin; p120(ctn); p120(cas) |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane, Cytoplasm |
| Accession | O60716 |
| Clone Number | SDT-350-75 |
| Antibody Type | Recombinant mAb |
| Application | ICFCM, IHC-P, ICC, WB, IF |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied. |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC | 1:500-1:1000 | |
| ICC | 1:1000 | |
| IF | 1:500 | |
| ICFCM | 1:500 |
Background
Catenin δ-1 (P120 Catenin) belongs to the β-serial protein family .p-120 catenin (along with α, β and γ catenins) connects the transmembrane protein E-cadherin to the actin cytoskeleton in the cell cytoplasm. It expresses in various normal epithelial tissues (including thyroid, breast, stomach, duodenal, liver, pancreas, colon, kidney, prostate, testicles), various non -epithelial tissues (including myocardial cells, neurons, gel cells To. p-120 regulates the transformation of calcium adhesion protein on the surface of the cells, thereby determining the E-calcium adhesive protein levels used in the cells, and then plays an important role in the adhesion of the cells. Many studies have shown that p-120 irregularly expression or lack of disobedience in a variety of cancer cells indicates that p-120 play a role in cancer-suppressing genes.
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