SKU: 39964078933

APC Mouse Anti-Human CD59 Antibody (S-R567)

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Description

APC Mouse Anti-Human CD59 Antibody (S-R567)Product Specification Host Mouse Antigen CD59 Synonyms CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor (HRF 20; HRF20); MAC inhibitory protein (MAC IP); MEM43 antigen; Membrane attack complex inhibition factor (MACIF); Membrane inhibitor of reactive lysis (MIRL); Protectin; MIC11; MIN1; MIN2; MIN3; MSK21 Location Secreted, Cell membrane Accession P13987 Clone Number S R567 Antibody Type Mouse mAb Isotype IgG2a Application FCM

Product Specification


Host Mouse
Antigen CD59
Synonyms CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor (HRF-20; HRF20); MAC-inhibitory protein (MAC-IP); MEM43 antigen; Membrane attack complex inhibition factor (MACIF); Membrane inhibitor of reactive lysis (MIRL); Protectin; MIC11; MIN1; MIN2; MIN3; MSK21
Location Secreted, Cell membrane
Accession P13987
Clone Number S-R567
Antibody Type Mouse mAb
Isotype IgG2a
Application FCM
Reactivity Hu
Positive Sample human peripheral blood cells
Purification Protein A
Concentration 0.2 mg/ml
Conjugation APC
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD59, also known as membrane inhibitor of reactive lysis (MIRL) or protectin, is a glycosylphosphatidylinositol (GPI)-anchored membrane protein that plays a crucial role in regulating the complement system, an essential part of the innate immune response. It is widely expressed on various human cells and tissues, including erythrocytes, leukocytes, fibroblasts, and epithelial cells. The primary function of CD59 is to inhibit the formation of the membrane attack complex (MAC), thereby preventing complement-mediated cell lysis. This protective mechanism is vital for maintaining cell integrity and preventing excessive immune-mediated damage.

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SKU: 39964078933

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4.6 ★★★★★
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Product Reviews
C
Verified Purchase
Cristobal
Lake Worth, US
★★★★★ 5
STELLAR
Format: Hardcover
Highest quality print. I ordered this book during the early part of the 2020 pandemic. When it arrived I was so happy. The images were comforting during a time of great stress in our world. It reminded me that Final Fantasy has been a tremendous part of my life. I'm grateful for the effort put into this book, which was in part a preview of the Pixel Remasters that came later. Brilliant.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 19, 2024
G
Verified Purchase
Gavin Duhé
Louisville, US
★★★★★ 4
Amazing book, but unnecessary
Format: Hardcover, Format: Hardcover
I would give this book 5 stars, but at the end of the day I don't think I can. I love flipping through it and looking at the color palettes and seeing the ways the artists communicated ideas through their limited palettes and spaces. There are also little 3D paper arts you can do of some of the sprites, like the fountain pictured above. It has helped me in my pixel art journey and it could 100% help you. The only reason I would say not to buy it is because all of the sprites are accessible online. If you want to understand the art on a deeper level and develop an appreciation for the passion that pixel art contains, buy it. If you want to look at them quickly as references and are an experienced pixel artist, it is not as useful, you could learn the rules just by looking at the sprites online, but you would miss the explanations and writings that help explain the art.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 12, 2023
C
Verified Purchase
Catdad
Draper, US
★★★★★ 5
Great for my Quilting!
Format: Hardcover, Format: Hardcover
I bought this book at launch and it has pretty much become my “bible” for Final Fantasy pixel art. I sew and love making nerdy quilts so when I saw this, it was a total insta-buy. It showcases so much original art as well as newly designed sprites (for both older and newer games). I honestly didn’t know about the newer games being designed as sprites so when I saw this, I immediately got to creating. Beyond this being a great pattern book for pixel quilting, I loved seeing a piece of FF history we don’t get to know about. Also loved the interview showcased. A good book for any Final Fantasy lover collection!
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Reviewed in the United States on October 16, 2020
M
Verified Purchase
Mykel Eddy
Grantham, US
★★★★★ 5
A great book for a fan of the early final fantasy series.
Format: Hardcover
I love this book! I grew up with the NES and this brought back a lot of memories of how as a kid I would get lost in the creativity of what developers of these games made with only some blocks. I love pixel art and this book is great if you enjoy making your own and admiring the work of someone else's and seeing their imagination from some truly great games. This book is small in size but is perfect size to show blown up images of final fantasy pixel characters and creatures, also of places from the games. Also having final fantasy characters from beyond the Nintendo/SNES was a really cool surprise to see if they had been made in that era.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 5, 2020
S
Verified Purchase
SerenaHtg
Massapequa, US
★★★★★ 5
Such a cool book!
Format: Hardcover, Format: Hardcover
A really awesome book, it's a must have for any final fantasy fan. So many pages(300!) for such little price. Beautifully made! It arrived in a hard package in perfect condition.
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Reviewed in the United States on October 14, 2023

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