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Description
IRF3 Recombinant Rabbit mAb (S-449-24)Product Specification Host Rabbit Synonyms Interferon regulatory factor 3, IRF 3 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession Q14653 Clone Number S 449 24 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IP Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months
Product Specification
| Host | Rabbit |
| Synonyms | Interferon regulatory factor 3, IRF-3 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus |
| Accession | Q14653 |
| Clone Number | S-449-24 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:2000 | |
| IP | 1:50 | |
| IHC-P | 1:250 |
Background
IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 plays an important role in the innate immune system's response to viral infection. It is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. The complex translocates into the nucleus for the transcriptional activation of interferons alpha and beta, and further interferon-induced genes.
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